Important contributor to respiratory diseases

Enzootic pneumonia, caused by Mycoplasma hyopneumoniae (M. hyo), is a costly, chronic and widespread disease that negatively impacts growth rate and feed efficiency. M. hyo damages the cilia and epithelia of the airways of the lower respiratory tract, making way for invasion by secondary pathogens. Viral infection can complicate the picture even further.

Interactions with other pathogens:

  • Pasteurella multocida
  • Streptococcus suis
  • Haemophilus parasuis (Glässers Disease)
  • Actinobacillus pleuropneumoniae
  • Porcine Reproductive and Respiratory Syndrome virus (PRRSv)
  • Porcine circovirus type 2 (PCV2) [Porcine Circovirus Diseases (PCVD)]
  • Swine influenza virus (SIV)


M. hyo is a common agent implicated in the development of Porcine Respiratory Disease Complex (PRDC). It is difficult to isolate and grows slowly in the laboratory. Small and filterable, it survives only a short time in swine housing environments and can be destroyed by most disinfectants. In pigs with pneumonia, it may be difficult to determine which agent is the primary pathogen. Evidence suggests that M. hyo increases the severity of several other infections, including PRRS and PCV2, and is capable of acting as a significant primary pathogen on its own.

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